Department of Material and Life Science, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Chemistry. 2012 Aug 13;18(33):10066-73. doi: 10.1002/chem.201200688. Epub 2012 Jun 28.
A twofold helix (2(1) helix) is an essential motif in approximately 70% of organic crystals. Although handedness of 2(1) helix has not been discussed from a mathematical viewpoint, we noticed that the handedness can be defined by considering the molecular shape and manner of assembly. Herein we propose the supramolecular-tilt-chirality (STC) method to define the handedness, and illustrate it by way of some examples. We believe that establishment of the systematic rules for supramolecular chirality will contribute to the progression of supramolecular chemistry and material science.
双螺旋（2(1)螺旋）是大约 70%有机晶体的基本结构。虽然从数学角度尚未讨论 2(1)螺旋的手性，但我们注意到手性可以通过考虑分子形状和组装方式来定义。在此，我们提出超分子倾斜手性（STC）方法来定义手性，并通过一些实例来说明。我们相信建立超分子手性的系统规则将有助于推动超分子化学和材料科学的发展。
