Kim Sung-Hoon, Kim Jun-Su, Choi Jae-Young, Lee Ka-Young, Park Tae-Jin, Lee Jae-Hwa
Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Korean J Fam Med. 2011 May;32(4):234-42. doi: 10.4082/kjfm.2011.32.4.234. Epub 2011 May 31.
Depressive symptoms accompanied by chronic obstructive pulmonary disease (COPD) can be influenced by socioeconomic status, associated chronic diseases and the current smoking status. This study was conducted to assess factors that are associated with depressive symptoms accompanied by COPD, using the data obtained from the Korea National Health and Nutritional Survey (KNHANES) conducted in 2005 and 2008.
From the third (2005) and the fourth (2008) KNHANES, 407 (0.9%) with physician-diagnosed COPD were selected. Of the 407 subjects, only 180 (0.4%) who reported having depressive symptoms were included in this study. The associations of depressive symptoms with socioeconomic status, associated chronic diseases and smoking status were investigated.
Of the total 180 subjects, 45 (25%) had depressive symptoms. There were 102 males (55%) and 78 females (45%) with a slight predilection for males. In multivariate analysis, significant predictors of depressive symptoms were dependent activities of daily living (odds ratio [OR], 2.42; 95% confidence interval [CI], 2.06 to 2.84) and association with number of chronic diseases (OR of one, two, and three, 1.40, 1.72, 2.60; 95% CI of one, two, and three, 1.20 to 1.63,1.41 to 2.10,1.99 to 3.39).
This study provides the basis for managing COPD patients in a clinical setting by understanding the number and characteristics of COPD patients with depressive symptoms. The results of this study suggest that primary physicians should manage COPD patients with consideration of risk factors for depressive symptom.
伴有慢性阻塞性肺疾病(COPD)的抑郁症状可能受到社会经济地位、相关慢性病及当前吸烟状况的影响。本研究利用2005年和2008年韩国国家健康与营养检查调查(KNHANES)所获数据,评估与伴有COPD的抑郁症状相关的因素。
从第三轮(2005年)和第四轮(2008年)KNHANES中,选取407名经医生诊断患有COPD的患者(占0.9%)。在这407名受试者中,本研究仅纳入了180名报告有抑郁症状的患者(占0.4%)。研究了抑郁症状与社会经济地位、相关慢性病及吸烟状况之间的关联。
在180名受试者中,45名(25%)有抑郁症状。其中男性102名(55%),女性78名(45%),男性略占多数。多因素分析显示,抑郁症状的显著预测因素为日常生活依赖活动(比值比[OR]为2.42;95%置信区间[CI]为2.06至2.84)以及与慢性病数量的关联(患一种、两种和三种慢性病的OR分别为1.40、1.72、2.60;95%CI分别为1.20至1.63、1.41至2.10、1.99至3.39)。
本研究通过了解伴有抑郁症状的COPD患者数量及特征,为临床环境中管理COPD患者提供了依据。本研究结果表明,基层医生在管理COPD患者时应考虑抑郁症状的危险因素。