Awada Adnan, Atallah David, Zoghbi Antoine
Service de Neurologie, CHU Hôtel-Dieu de France, Beyrouth, Liban.
J Med Liban. 2011 Oct-Dec;59(4):233-4.
Yellow lupine seeds (Tourmos) are frequently used as snack in Lebanon but their potential toxicity is extremely rare (five published cases) and often undiagnosed.
Two patients presented with anticholinergic syndrome (mydriasis, mouth dryness, palpitations, general malaise) after ingestion of 200-500 g of bitter lupine seeds (not soaked enough in water). No other cause of intoxication was found, and symptoms disappeared spontaneously in 24-36h.
Yellow lupine seeds need a long preparation (boiling then soaking with several changes of water) to debitter before consumption. The spontaneous bitter taste is mainly due to the presence of a toxic substance with anticholinergic properties, lupanine. An insufficient preparation or a preference for bitter lupin can result in intoxication.
黄羽扇豆种子(Tourmos)在黎巴嫩常被用作零食,但它们潜在的毒性极为罕见(已发表五例病例),且常常未被诊断出来。
两名患者在摄入200 - 500克苦羽扇豆种子(未充分用水浸泡)后出现抗胆碱能综合征(瞳孔散大、口干、心悸、全身不适)。未发现其他中毒原因,症状在24 - 36小时内自行消失。
黄羽扇豆种子在食用前需要长时间处理(先煮沸然后多次换水浸泡)以去除苦味。其天然的苦味主要归因于一种具有抗胆碱能特性的有毒物质——金雀花碱。处理不充分或偏爱苦羽扇豆会导致中毒。