Tsiodras S, Shin R K, Christian M, Shaw L M, Sass D A
Department of Internal Medicine, Albert Einstein Medical Center, University of Pennsylvania, Philadelphia, PA, USA.
Ann Emerg Med. 1999 Jun;33(6):715-7.
We describe a case of sparteine intoxication associated with using a preparation from lupine seeds. A female patient of Portuguese origin presented to the emergency department with classic anticholinergic signs after ingestion of a lupine seed extract. She took the preparation with the belief it represented a cure for her recently diagnosed diabetes. Analysis of the patient's lupine bean extract identified the preponderant compound as oxo-sparteine by gas chromatography/mass spectrometry. Intoxication by lupine seeds rarely occurs in human beings. To our knowledge, no medical or toxicologic evidence supports a belief that lupine extract could lower serum glucose levels. This case highlights the need for emergency care providers to be aware of the health hazards that can be associated with the use of such home remedies.
我们描述了一例与食用羽扇豆种子制剂相关的鹰爪豆中毒病例。一名葡萄牙裔女性患者在摄入羽扇豆种子提取物后，因出现典型的抗胆碱能体征而被送往急诊科。她服用该制剂是因为相信它能治愈她最近被诊断出的糖尿病。通过气相色谱/质谱法对患者的羽扇豆提取物进行分析，确定主要化合物为氧代鹰爪豆碱。羽扇豆种子中毒在人类中很少发生。据我们所知，没有医学或毒理学证据支持羽扇豆提取物能降低血糖水平这一观点。该病例凸显了急诊医护人员需要意识到使用此类民间疗法可能带来的健康危害。
