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回顾性研究了在科索沃大学临床中心(2005-2010 年)治疗的 22 例坏死性筋膜炎患者。

A retrospective study of 22 patients with necrotising fasciitis treated at the University Clinical Center of Kosovo (2005-2010).

机构信息

Department of Plastic Surgery, University Clinical Center of Kosovo, Prishtina.

出版信息

Int Wound J. 2013 Aug;10(4):461-5. doi: 10.1111/j.1742-481X.2012.01005.x. Epub 2012 Jul 3.

Abstract

Necrotising fasciitis (NF) is a destructive invasive infection of skin, subcutaneous tissue and deep fascia. The aim of the study is to determine the causative agents of NF, its localisation, predisposing factors and comorbid conditions, duration of treatment and distribution of NF in different age groups and over the years. We conducted a retrospective study including 22 patients with NF from 2005 to 2010 in the University Clinical Center of Kosovo. The data were collected and analysed from the archives and protocols of the University Clinical Center of Kosovo. The average age of patients was 56·9 years. In eight cases or 36·4% of total patients studied, NF was caused by monobacterial agents with a predominance of Pseudomonas aeruginosa (five cases or 22·7% of total infections). Polybacterial agents were responsible for NF infection in other 14 cases (63·6%). Majority of the patients had other comorbidities like diabetes, trauma and prior history of surgical interventions. Diabetes was present in 17 patients or 77·3%. The remaining five patients (22·7%) had previous trauma and recent surgical intervention. Average length of treatment was 43 days. The hospital mortality rate in our case series was 22·6%. Early identification and diagnosis of NF significantly improves outcome and reduces mortality.

摘要

坏死性筋膜炎(NF)是一种破坏性的皮肤、皮下组织和深筋膜的侵袭性感染。本研究旨在确定 NF 的病原体、其定位、易患因素和合并症、治疗时间以及不同年龄组和多年来 NF 的分布情况。我们进行了一项回顾性研究,纳入了 2005 年至 2010 年期间在科索沃大学临床中心的 22 名 NF 患者。数据是从科索沃大学临床中心的档案和方案中收集和分析的。患者的平均年龄为 56.9 岁。在 22 名患者中,有 8 名(36.4%)或总患者的 8 名(36.4%)因单细菌病原体引起 NF,其中以铜绿假单胞菌为主(5 例或总感染的 22.7%)。多细菌病原体在其他 14 例(63.6%)患者中引起 NF 感染。大多数患者有其他合并症,如糖尿病、创伤和先前的手术干预史。17 名患者(77.3%)有糖尿病。其余 5 名患者(22.7%)有先前的创伤和最近的手术干预。平均治疗时间为 43 天。在我们的病例系列中,医院死亡率为 22.6%。早期识别和诊断 NF 可显著改善预后,降低死亡率。

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本文引用的文献

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Mortality in necrotizing fasciitis.坏死性筋膜炎中的死亡率。
J Ayub Med Coll Abbottabad. 2008 Apr-Jun;20(2):96-8.
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The diagnosis of necrotizing fasciitis.坏死性筋膜炎的诊断。
Curr Opin Infect Dis. 2005 Apr;18(2):101-6. doi: 10.1097/01.qco.0000160896.74492.ea.

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