Department of Medical Psychology, University Medical Center Hamburg-Eppendorf, Germany.
Behav Res Ther. 2012 Sep;50(9):580-7. doi: 10.1016/j.brat.2012.04.005. Epub 2012 May 15.
We investigated the comparative effectiveness of cognitive-behavioural (CBT) and psychodynamic therapy (PDT) under clinically representative conditions as a subtrial of a prior study (Watzke et al., 2010, BJP). A consecutive sample of 147 patients with common mental disorders was randomised to either CBT or PDT in routine mental health care. In a primary per-protocol analysis patients randomised to CBT had a significantly better longer term outcome in the primary outcome symptom severity (General Severity Index of the SCL-14; p=.001; partial η(2)=0.073) as well as in health related quality of life (Mental Component Summary of the SF-8; p=.013; partial η(2)=.041) and concerning interpersonal issues (Inventory of Interpersonal Problems, IIP-C; p=.001; partial η(2)=.070) 6 months after treatment than patients randomised to PDT. These results could be confirmed in intention-to-treat analyses (n=180) suggesting that there was no substantial attrition bias due to drop outs at the follow-up assessment. Thus, the so called equivalence outcome paradox was not replicated in this study.
我们在临床代表性条件下研究了认知行为疗法(CBT)和心理动力学疗法(PDT)的比较效果,这是先前研究(Watzke 等人,2010,BJP)的一个子研究。147 名常见精神障碍患者的连续样本被随机分配到常规心理健康护理中的 CBT 或 PDT 组。在主要的按方案分析中,随机分配到 CBT 的患者在主要结局症状严重程度(SCL-14 的一般严重程度指数;p=.001;部分η²=0.073)以及健康相关生活质量(SF-8 的心理成分综合评分;p=.013;部分η²=0.041)和人际关系问题(人际关系问题清单,IIP-C;p=.001;部分η²=0.070)方面的长期结局显著更好,比随机分配到 PDT 的患者更好。这些结果在意向治疗分析(n=180)中得到了证实,这表明由于在随访评估时的脱落,没有实质性的损耗偏差。因此,在这项研究中,所谓的等效结果悖论没有被复制。