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信号转导蛋白TRAP(RNAIII激活蛋白的靶点)的结构

Structure of the signal transduction protein TRAP (target of RNAIII-activating protein).

作者信息

Henrick Kim, Hirshberg Miriam

机构信息

Research Collaboratory for Structural Bioinformatics Protein Data Bank, Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 610 Taylor Road, Piscataway, NJ 08854-8087, USA.

出版信息

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):744-50. doi: 10.1107/S1744309112020167. Epub 2012 Jun 22.

Abstract

The crystal structure of the signal transduction protein TRAP is reported at 1.85 Å resolution. The structure of TRAP consists of a central eight-stranded β-barrel flanked asymmetrically by helices and is monomeric both in solution and in the crystal structure. A formate ion was found bound to TRAP identically in all four molecules in the asymmetric unit.

摘要

信号转导蛋白TRAP的晶体结构以1.85 Å的分辨率被报道。TRAP的结构由一个中央八链β桶组成,其两侧不对称地排列着螺旋,并且在溶液和晶体结构中均为单体。在不对称单元的所有四个分子中,均发现有一个甲酸根离子以相同方式与TRAP结合。

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