Bobrov V A, Vitokhina L I
Vrach Delo. 1990 Apr(4):45-8.
A study of 115 patients with rheumatic heart disease associated with arterial hypertension revealed significant changes of functioning of depressor kallikrein-kinin system of the kidneys and blood. The period of formation of arterial hypertension is already distinguished by an exhaustion of the depressor systems manifested in a marked reduction of the kallikrein excretion in response to physical loads and a reduction of the extracellular volume deteriorating in the course of stabilization of arterial hypertension.
一项针对115例患有风湿性心脏病合并动脉高血压患者的研究显示，肾脏和血液中的降压激肽释放酶 - 激肽系统功能发生了显著变化。动脉高血压形成期的特征已经表现为降压系统耗竭，表现为对体力负荷的激肽释放酶排泄显著减少，以及在动脉高血压稳定过程中细胞外液量减少。
