Brouwer Derk H
TNO Research Group Quality and Safety, PO Box 360, 3700 AJ Zeist, The Netherlands.
Ann Occup Hyg. 2012 Jul;56(5):506-14. doi: 10.1093/annhyg/mes039.
Control banding (CB) has been developed as a pragmatic tool to manage the risk resulting from exposure to a wide variety of potentially hazardous substances in the absence of firm toxicological and exposure information. Currently, the CB approach is applied for emerging risks such as nanoparticles, by the development of various CB-based tools. Six of these are compared. Despite their similarity, i.e. combining hazard and exposure into control or risk bands, the structure, the applicability domains, and the assignment of the hazard and exposure bands, show differences that may affect the consistency of the resulting outcome amongst the various CB tools. The value of the currently available CB tools for nanomaterials can be enhanced by transparently elucidating these differences for user consideration during the selection of a tool for a specific scenario of application.
控制带(CB)已被开发为一种实用工具,用于在缺乏确凿的毒理学和暴露信息的情况下,管理因接触多种潜在有害物质而产生的风险。目前,通过开发各种基于控制带的工具,控制带方法被应用于纳米颗粒等新兴风险。对其中六种工具进行了比较。尽管它们有相似之处,即将危害和暴露合并到控制或风险带中,但结构、适用领域以及危害和暴露带的划分存在差异,这些差异可能会影响不同控制带工具所得结果的一致性。通过在为特定应用场景选择工具时,透明地阐明这些差异以供用户考虑,可以提高当前可用的纳米材料控制带工具的价值。