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Stoffenmanager纳米版1.0:一种用于对空气中人造纳米物体进行风险优先级排序的基于网络的工具。

Stoffenmanager Nano version 1.0: a web-based tool for risk prioritization of airborne manufactured nano objects.

作者信息

Van Duuren-Stuurman Birgit, Vink Stefan R, Verbist Koen J M, Heussen Henri G A, Brouwer Derk H, Kroese Dinant E D, Van Niftrik Maikel F J, Tielemans Erik, Fransman Wouter

机构信息

TNO Innovation for Life, Utrechtseweg 48, PO Box 350, 3700 AJ Zeist, The Netherlands.

出版信息

Ann Occup Hyg. 2012 Jul;56(5):525-41. doi: 10.1093/annhyg/mer113. Epub 2012 Jan 20.

Abstract

Stoffenmanager Nano (version 1.0) is a risk-banding tool developed for employers and employees to prioritize health risks occurring as a result of exposure to manufactured nano objects (MNOs) for a broad range of worker scenarios and to assist implementation of control measures to reduce exposure levels. In order to prioritize the health risks, the Stoffenmanager Nano combines the available hazard information of a substance with a qualitative estimate of potential for inhalation exposure. The development of the Stoffenmanager Nano started with a review of the available literature on control banding. Input parameters for the hazard assessment of MNOs were selected based on the availability of these parameters in, for instance, Safety Data Sheets or product information sheets. The conceptual exposure model described by Schneider et al. (2011) was used as the starting point for exposure banding. During the development of the Stoffenmanager Nano tool, the precautionary principle was applied to deal with the uncertainty regarding hazard and exposure assessment of MNOs. Subsequently, the model was converted into an online tool (http://nano.stoffenmanager.nl), tested, and reviewed by a number of companies. In this paper, we describe the Stoffenmanager Nano. This tool offers a practical approach for risk prioritization in exposure situations where quantitative risk assessment is currently not possible. Updates of this first version are anticipated as more data become available in the future.

摘要

纳米材料管理工具(版本1.0)是一种风险分级工具,为雇主和员工开发,用于对在广泛的工作场景中因接触人造纳米物体(MNO)而产生的健康风险进行优先级排序,并协助实施控制措施以降低接触水平。为了对健康风险进行优先级排序,纳米材料管理工具将一种物质的现有危害信息与吸入接触可能性的定性估计相结合。纳米材料管理工具的开发始于对控制分级现有文献的综述。基于例如安全数据表或产品信息表中这些参数的可用性,选择了用于MNO危害评估的输入参数。施耐德等人(2011年)描述的概念性接触模型被用作接触分级的起点。在纳米材料管理工具的开发过程中,应用了预防原则来处理关于MNO危害和接触评估的不确定性。随后,该模型被转换为在线工具(http://nano.stoffenmanager.nl),并由多家公司进行了测试和审查。在本文中,我们描述了纳米材料管理工具。该工具为当前无法进行定量风险评估的接触情况中的风险优先级排序提供了一种实用方法。随着未来可获得更多数据,预计会对该第一版进行更新。

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