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韩国人群全景片上颈动脉钙化的流行率及相关性与外周动脉疾病:东固研究。

The prevalence and correlation of carotid artery calcification on panoramic radiographs and peripheral arterial disease in a population from the Republic of Korea: the Dong-gu study.

机构信息

Department of Oral and Maxillofacial Radiology, School of Dentistry, Dental Science Institute, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757, Republic of Korea.

出版信息

Dentomaxillofac Radiol. 2013;42(3):29725099. doi: 10.1259/dmfr/29725099. Epub 2012 Jun 29.

Abstract

OBJECTIVES

The aim of this study was to determine the prevalence of carotid artery calcification (CAC) detected on panoramic radiographs and peripheral arterial disease (PAD), and to evaluate the difference in the prevalence of PAD between patients with CAC and patients without CAC detectable by panoramic radiograph.

METHODS

The surveyed population consisted of 4078 subjects aged 50 years and older (1410 males and 2668 females) who underwent medical and dental examination in Gwangju city, South Korea. Two oral and maxillofacial radiologists interpreted the panoramic radiographs for the presence of carotid artery calcification. A trained research technician measured the ankle-brachial index (ABI). An ABI <0.9 in either leg was considered evidence of PAD.

RESULTS

The prevalence of CAC on panoramic radiographs was 6.2% and that of PAD was 2.6%. Subjects with CAC had a significantly higher prevalence of PAD than those without CAC (5.5% vs 2.4%, respectively). The presence of CAC on panoramic radiographs was associated with PAD (odds ratio 1.84; 95% confidence interval 1.01-3.36) after adjusting for potential confounders.

CONCLUSION

CACs detected on panoramic radiographs were positively associated with PAD in middle-aged and older Korean adults.

摘要

目的

本研究旨在确定全景放射片中检测到的颈动脉钙化(CAC)和外周动脉疾病(PAD)的患病率,并评估 CAC 可检测和不可检测的患者之间 PAD 的患病率差异。

方法

该研究调查了韩国光州市年龄在 50 岁及以上的 4078 名受试者(男性 1410 名,女性 2668 名),他们接受了医学和牙科检查。两名口腔颌面放射科医生对全景放射片中是否存在颈动脉钙化进行了解读。经过培训的研究技术人员测量了踝肱指数(ABI)。任何一条腿的 ABI<0.9 被认为存在 PAD。

结果

全景放射片中 CAC 的患病率为 6.2%,PAD 的患病率为 2.6%。有 CAC 的患者 PAD 的患病率明显高于无 CAC 的患者(分别为 5.5%和 2.4%)。在调整了潜在混杂因素后,全景放射片中 CAC 的存在与 PAD 相关(比值比 1.84;95%置信区间 1.01-3.36)。

结论

在中年和老年韩国成年人中,全景放射片中检测到的 CAC 与 PAD 呈正相关。

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