Department of Internal Medicine, Nephrology and Dialysotherapy, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warsaw 44, Poland,
Int Urol Nephrol. 2013 Oct;45(5):1489-94. doi: 10.1007/s11255-012-0210-4. Epub 2012 Jul 1.
Mantle cell lymphoma (MCL) is a rare aggressive lymphoid neoplasm occurring in about 3-7 % of non-Hodgkin lymphomas in the United States and Europe. Although lymphomas infiltrations are recognized in about half of post-mortem studies, in available literature we found only eight cases of mantle cell lymphoma with renal involvement. Five of them present MCL related glomerulonephritis, two show renal MCL infiltration with acute kidney injury and the last one describes MCL infiltration with acute tubulo-intrerstitial nephritis. We present the first case of a patient with the coexistence of renal mantle cell lymphoma infiltration, subacute membranoproliferative glomerulonephritis and acute kidney injury.
套细胞淋巴瘤(Mantle cell lymphoma,MCL)是一种罕见的侵袭性淋巴肿瘤,在美国和欧洲约占非霍奇金淋巴瘤的 3-7%。尽管尸检研究中约有一半可发现淋巴瘤浸润,但在现有文献中,我们仅发现 8 例伴有肾脏受累的套细胞淋巴瘤。其中 5 例表现为与 MCL 相关的肾小球肾炎,2 例表现为伴有急性肾损伤的肾 MCL 浸润,最后 1 例描述了伴有急性肾小管间质性肾炎的 MCL 浸润。我们报告首例同时存在肾套细胞淋巴瘤浸润、亚急性膜增殖性肾小球肾炎和急性肾损伤的患者。