Etta Praveen Kumar, Rao M V, Reddy Sujeet, Gowrishankar Swarnalata, Agarwal Neha
Department of Nephrology and Renal Transplantation, Virinchi Hospitals, Hyderabad, Telangana, India.
Department of Nephrology, Asian Institute of Nephrology and Urology, Hyderabad, Telangana, India.
Indian J Nephrol. 2020 May-Jun;30(3):192-195. doi: 10.4103/ijn.IJN_160_19. Epub 2020 Feb 11.
Mantle cell lymphoma (MCL) is a rare aggressive lymphoproliferative disorders (LPD) of B-cell lymphoma, which usually presents in advanced stages at initial diagnosis. Renal involvement in MCL is very rare, especially the combined presence of both glomerular and interstitial disease. We report on a patient with lymphomatous interstitial nephritis (LIN) coexistent with paraneoplastic crescentic membranoproliferative glomerulonephritis (MPGN), subsequently diagnosed to have disseminated MCL with bone marrow and lymph nodal infiltration. He was treated with rituximab-based chemotherapy and went into complete renal remission at 6-months of follow up.
套细胞淋巴瘤（MCL）是一种罕见的侵袭性B细胞淋巴瘤淋巴增殖性疾病（LPD），初诊时通常处于晚期。MCL累及肾脏非常罕见，尤其是肾小球和间质疾病同时存在的情况。我们报告了一例患有淋巴瘤性间质性肾炎（LIN）并伴有副肿瘤性新月体性膜增生性肾小球肾炎（MPGN）的患者，随后诊断为伴有骨髓和淋巴结浸润的播散性MCL。他接受了以利妥昔单抗为基础的化疗，随访6个月时肾脏完全缓解。
