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[角膜厚度对后弹力层剥除自动内皮角膜移植术(DSAEK)后眼压测量的影响]

[Influence of corneal thickness on intraocular pressure measurements following Descemet's stripping automated endothelial keratoplasty (DSAEK)].

作者信息

Klamann M K J, Maier A-K B, Gonnermann J, Torun N, Ruokonen P C

机构信息

Department of Ophthalmology, University Medicine Charité Berlin, Augustenburger Platz 1, 13353, Berlin, Deutschland.

出版信息

Ophthalmologe. 2012 Nov;109(11):1093-7. doi: 10.1007/s00347-012-2623-y.

Abstract

BACKGROUND

The aim of this study was to evaluate the effect of increased corneal thickness after Descemet's stripping automated endothelial keratoplasty (DSAEK) on intraocular pressure (IOP) measured by four different techniques.

METHODS

In this study 30 eyes from 30 patients with successful DSAEK treatment (group 1) and 30 eyes of 30 healthy subjects (group 2) were enrolled. The IOP was measured with iCare, IOPen, Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) techniques. Central corneal thickness (CCT) was measured by ultrasonic pachymetry. These data were used for statistical analysis.

RESULTS

The mean IOP measured by GAT, DCT, iCare and IOPen was 13.2, 16.1, 12.5 and 14.2 mmHg in group 1 and 13.4, 14.4, 14.4 and 13.3 mmHg in group 2, respectively. Correlations between IOP and CCT were not statistically significant in either group.

CONCLUSION

The results of IOP measurements by the iCare, IOPen, GAT and DCT techniques seem to be unrelated to artificially thickened corneas after DSAEK. In spite of partially good correlation between the four techniques a direct exchange of the devices is not recommended on account of the wide dispersion of values.

摘要

背景

本研究的目的是评估后弹力层剥脱自动内皮角膜移植术(DSAEK)后角膜厚度增加对通过四种不同技术测量的眼压(IOP)的影响。

方法

本研究纳入了30例DSAEK治疗成功患者的30只眼(第1组)和30名健康受试者的30只眼(第2组)。使用iCare、IOPen、Goldmann压平眼压计(GAT)和动态轮廓眼压计(DCT)技术测量眼压。通过超声测厚法测量中央角膜厚度(CCT)。这些数据用于统计分析。

结果

第1组中,通过GAT、DCT、iCare和IOPen测量的平均眼压分别为13.2、16.1、12.5和14.2 mmHg,第2组中分别为13.4、14.4、14.4和13.3 mmHg。两组中眼压与CCT之间的相关性均无统计学意义。

结论

iCare、IOPen、GAT和DCT技术测量眼压的结果似乎与DSAEK后人工增厚的角膜无关。尽管这四种技术之间部分存在良好的相关性,但由于测量值的广泛分散,不建议直接更换设备。

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