Bochmann F, Kaufmann C, Becht C, Bachmann L M, Thiel M A
Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne, Switzerland.
Klin Monbl Augenheilkd. 2009 Apr;226(4):241-4. doi: 10.1055/s-0028-1109242. Epub 2009 Apr 21.
Intraocular pressure (IOP) measurements using Goldmann applanation tonometry (GAT) are influenced by central corneal thickness (CCT) whereas dynamic contour tonometry (DCT) allows for IOP measurements independent of CCT. After Descemet's stripping automated endothelial keratoplasty (DSAEK) the CCT is, compared to healthy eyes, increased. The objective of this prospective study was to compare IOP measurements obtained by DCT and GAT in patients after a DSAEK procedure.
DCT and GAT were performed 3 and/or 6 months after DSAEK. Comparison of means was performed using the Wilcoxon signed-ranks test.
In total, 50 IOP measurements on 33 eyes were obtained. Mean CCT was 621 (+/- 60) microm. Overall correlation between GAT and DCT was good, however, in some patients a remarkable difference between pressure readings of up to 10.8 mmHg was observed. Mean IOP readings obtained by DCT were significantly higher (20.9 +/- 5.9 mmHg) than those obtained by GAT (19.1 +/- 6.5 mmHg; p = 0.0002). However, the difference between GAT and DCT readings was not influenced by the thickness of the transplanted lamella.
The well-known difference in mean pressure readings between DCT and GAT was not affected by the increase in CCT following DSAEK. IOP readings with the GAT seem not to be influenced by the increase in CCT. Because of the remarkable differences in individual pairs of IOP measurements, both GAT and DCT should be used after DSAEK.
使用Goldmann压平眼压计(GAT)测量眼压受中央角膜厚度(CCT)影响,而动态轮廓眼压计(DCT)可独立于CCT测量眼压。与健康眼相比,Descemet膜剥离自动内皮角膜移植术(DSAEK)后CCT增加。本前瞻性研究的目的是比较DSAEK术后患者通过DCT和GAT获得的眼压测量值。
在DSAEK术后3个月和/或6个月进行DCT和GAT测量。使用Wilcoxon符号秩检验进行均值比较。
共获得33只眼的50次眼压测量值。平均CCT为621(±60)微米。GAT和DCT之间的总体相关性良好,然而,在一些患者中观察到眼压读数之间存在高达10.8 mmHg的显著差异。DCT获得的平均眼压读数(20.9±5.9 mmHg)显著高于GAT获得的读数(19.1±6.5 mmHg;p = 0.0002)。然而,GAT和DCT读数之间的差异不受移植薄片厚度的影响。
DSAEK后CCT增加并未影响DCT和GAT之间众所周知的平均压力读数差异。GAT的眼压读数似乎不受CCT增加的影响。由于个体眼压测量值之间存在显著差异,DSAEK术后应同时使用GAT和DCT。