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[Various aspects of production of a therapeutic form of liposomal cytarabine].

作者信息

Pleteneva O P, Oksinoĭd O E, Afonin N I

出版信息

Vestn Akad Med Nauk SSSR. 1990(8):33-4.

PMID:2275274
Abstract

In the process of preparation of the liposomal cytostatic drug cytarabine for intravenous injection, the influences of the lipid composition of liposomes, the cryoprotector, and the technique of its administration on the liposome intactness were studied by HPLC. It was shown, that under certain conditions the use of definite components allows for preparing a dosage form of lyophylized sterile liposomal cytarabine capable of being stored for a year.

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