Nesytova N Iu, Paleva N S, Il'ina E V, Shenk P, Bendas F, Nun P
Vestn Akad Med Nauk SSSR. 1990(6):8-19.
The review embraces major trends and tendencies in liposome studies and is based on the statistical and qualitative analysis of patent information issued in the period 1970-1988. Special attention is devoted to the analysis of patents in liposome production techniques, their lipid composition, and application in pharmaceutical and cosmetic industries and also for the diagnostic and therapeutic purposes. Liposomal preparations are shown to be superior to common drugs as concerns, in particular, liposomes containing medicinal agents for prolonged use (including hormones, antibiotics, cytostatics, and immunostimulants) and liposomes used in dermatological practice. Liposome-based assessment of application prospects is given.
本综述涵盖了脂质体研究的主要趋势，并基于对1970年至1988年期间发布的专利信息的统计和定性分析。特别关注脂质体生产技术、其脂质组成以及在制药和化妆品行业中的应用，以及诊断和治疗用途方面的专利分析。脂质体制剂被证明在某些方面优于普通药物，特别是含有用于长期使用的药物（包括激素、抗生素、细胞抑制剂和免疫刺激剂）的脂质体以及用于皮肤科实践的脂质体。给出了基于脂质体的应用前景评估。
