Dikiĭ I L, Strel'nikov L S, Chueshov V I, Iakovenko V D, Bazavluk A D
Vestn Akad Med Nauk SSSR. 1990(6):40-4.
The possibility of using ectericide, having antibacterial, detergent, antioxidative, and reparative effects, as a dispersion medium for liposome production has been studied. Its application allows for elaboration of a simplified liposome production technique simultaneously imparting them stability against oxidation, heating, and pH changes. A technology to produce multivesicular liposomes with ectericide++, containing rifampicin in the membranous envelope and gentamicin in the inner volume, has been developed. Liposomal antibiotics proved to be effective in clinical trials.
已研究了使用具有抗菌、去污、抗氧化和修复作用的杀菌剂作为脂质体生产分散介质的可能性。其应用有助于开发一种简化的脂质体生产技术，同时赋予它们抗氧化、抗热和抗pH变化的稳定性。已开发出一种生产多泡脂质体的技术，该脂质体含有杀菌剂++，在膜包膜中含有利福平，在内腔中含有庆大霉素。脂质体抗生素在临床试验中证明是有效的。
