DePaul University, Chicago, IL 60614, USA.
J Clin Psychol. 2012 Sep;68(9):1028-35. doi: 10.1002/jclp.21880. Epub 2012 Jun 29.
This study sought to examine long-term health, symptom, and disability outcomes among patients with chronic fatigue syndrome (CFS) by comparing those diagnosed with CFS 25 years ago with healthy controls.
Of the 25 participants diagnosed with CFS 25 years ago, 5 self-reported that they maintained a diagnosis of CFS, while 20 reported no longer having a diagnosis. These two groups were compared with healthy controls on outcomes related to functioning and symptom severity.
Those who remitted from CFS showed significantly more impairment on 21 out of 23 outcomes compared with controls. On 17 outcomes, those who remitted had nonsignificant differences in impairment compared to those who maintained a CFS diagnosis.
Findings from this study suggest that over time many individuals will not maintain a CFS diagnosis but will not return to their premorbid level of functioning.
本研究通过比较 25 年前被诊断为慢性疲劳综合征 (CFS) 的患者与健康对照组，旨在研究 CFS 患者的长期健康、症状和残疾结局。
在 25 名 25 年前被诊断为 CFS 的参与者中，有 5 名自我报告维持 CFS 诊断，而 20 名报告不再有诊断。这两组与健康对照组在与功能和症状严重程度相关的结果上进行比较。
与对照组相比，从 CFS 中缓解的患者在 23 项结果中的 21 项上表现出明显更多的障碍。在 17 项结果中，与维持 CFS 诊断的患者相比，从 CFS 中缓解的患者在障碍方面的差异没有统计学意义。
本研究的结果表明，随着时间的推移，许多人不会维持 CFS 的诊断，但不会恢复到发病前的功能水平。
