Dipartimento di Medicina Trasfusionale ed Ematologia, Azienda Ospedaliera C. Poma, Mantova, Italy.
Semin Thromb Hemost. 2012 Jul;38(5):463-8. doi: 10.1055/s-0032-1305781. Epub 2012 Mar 6.
The Gram-negative bacterium Helicobacter pylori has a well-demonstrated role in several gastroduodenal diseases, including peptic ulcer disease, chronic active gastritis, mucosa-associated lymphoid tissue lymphoma, and gastric adenocarcinoma. In addition, more recently, several studies have focused on the possible causal role of H. pylori in various extragastric disorders, such as cardiovascular, respiratory, neurological, skin, and autoimmune conditions. The current status of the research on the pathogenesis, clinical and therapeutic aspects of H. pylori-associated idiopathic thrombocytopenic purpura in adults and children will be addressed in this narrative review.
革兰氏阴性细菌幽门螺杆菌在几种胃十二指肠疾病中具有明显的作用，包括消化性溃疡病、慢性活动性胃炎、黏膜相关淋巴组织淋巴瘤和胃腺癌。此外，最近的几项研究还集中在幽门螺杆菌在各种胃外疾病中的可能因果作用上，如心血管、呼吸、神经、皮肤和自身免疫性疾病。本叙述性综述将讨论成人和儿童中与幽门螺杆菌相关特发性血小板减少性紫癜的发病机制、临床和治疗方面的研究现状。
