North Orissa University, Baripada, India.
Indian J Microbiol. 2011 Jul;51(3):363-8. doi: 10.1007/s12088-011-0133-2. Epub 2011 Jan 25.
In vitro antibacterial activities of acetone, ethanol, methanol and water extracts of leaves and bark of Croton roxburghii L. studied against ten human pathogenic bacterial strains showed significantly higher activity in acetone extract and least activity in case of aqueous. Minimal inhibitory concentration (MIC) values of all extracts ranged between 0.62 and 10 mg/ml, while minimal bactericidal concentration (MBC) values ranged from 1.25 to values greater than 10 mg/ml. The antioxidant assays viz. DPPH, hydrogen peroxide scavenging, iron reducing and iron chelating assays along with total phenol and ascorbic acid content were carried out with aqueous extracts of leaves and bark. While the total phenol contents in leaves and bark extracts were 0.766 ± 0.014 and 0.735 ± 0.028% respectively their ascorbic acid contents were found to be 0.252 ± 0.019 and 0.431 ± 0.013% respectively. DPPH activities in both (leaves and bark) extracts increased with the increase in concentrations. Iron chelating capacity of leaves extract is significantly higher than that of the bark. Leaves extract showed an increase in percentage of scavenging property with the increase in concentrations. Plant extracts showed low amount of iron reducing property at all concentrations. Hydrogen peroxide scavenging properties of bark was low than that of the leaves.
体外抗菌活性的丙酮、乙醇、甲醇和水提取物的叶子和树皮的 Croton roxburghii L. 研究对十种人类致病菌株表现出明显更高的活性在丙酮提取物和最小活性在水的情况下。最小抑菌浓度（MIC）的所有提取物之间的 0.62 和 10 毫克/毫升，而最小杀菌浓度（MBC）值范围从 1.25 到值大于 10 毫克/毫升。抗氧化剂 assaysviz. DPPH、过氧化氢清除、铁还原和铁螯合 assays 以及总酚和抗坏血酸含量进行了叶子和树皮的水提取物。虽然叶子和树皮提取物中的总酚含量分别为 0.766 ± 0.014 和 0.735 ± 0.028%，其抗坏血酸含量分别为 0.252 ± 0.019 和 0.431 ± 0.013%。DPPH 活动在两个（叶和树皮）提取物的浓度增加而增加。叶子提取物的铁螯合能力明显高于树皮。叶提取物显示出增加的百分比与浓度增加清除性能。植物提取物在所有浓度下表现出低铁还原能力。过氧化氢清除性能的树皮比树叶低。
