Jain V K, Lal Harbans
Indian J Clin Biochem. 2011 Jul;26(3):309-11. doi: 10.1007/s12291-011-0132-4. Epub 2011 May 4.
Serum CRP and uric acid levels were estimated in twenty-five patients with psoriasis (group III) before and after 12 weeks of treatment. Results were compared with a group of 25 normal subjects (group I) and a group of 25 patients of various skin diseases other than psoriatic lesion (group II). Mean value for CRP was found to be increased by more than 20 folds in patients with psoriasis, which was subsequently reduced to nearly 50% of the initial value after 12 weeks of treatment. These patients also showed hyperuricemia. Nearly 25% of these patients also exhibited arthritis. It is thus suggested that both CRP and uric acid levels should be monitored in patients with psoriasis.
在25例银屑病患者(III组)治疗前及治疗12周后测定血清CRP和尿酸水平。将结果与25名正常受试者(I组)和25名除银屑病皮损外患有各种皮肤病的患者(II组)进行比较。发现银屑病患者的CRP平均值增加了20多倍,治疗12周后随后降至初始值的近50%。这些患者还表现为高尿酸血症。近25%的这些患者还表现出关节炎。因此建议对银屑病患者监测CRP和尿酸水平。