使用阿多装置经导管封堵动脉导管未闭：149例患者的回顾性研究
Transcatheter closure of patent ductus arteriosus using ado device: retrospective study of 149 patients.
作者信息
Al-Hamash Sadiq M, Wahab Hussein Abdul, Khalid Zayir H, Nasser Isam V
机构信息
Department of Pediatric Cardiology, College of Medicine, Al-Mustansiriya University, Baghdad, Iraq.
出版信息
Heart Views. 2012 Jan;13(1):1-6. doi: 10.4103/1995-705X.96658.
BACKGROUND
Patent ductus arteriosus (PDA) is a common form of congenital heart disease and forms about 5-10% of congenital heart diseases. Surgical closure is safe and effective; however, certain patients may experience some morbidity. Recently, transcatheter closure of PDA using the Amplatzer duct occluder has been shown to be safe and efficacious.
OBJECTIVES
To evaluate whether transcatheter closure with this device offers an alternative to surgical closure of PDA.
PATIENTS AND METHODS
Between July 2006 to July 2008, 149 patients (98 females and 51 males) with PDA underwent cardiac catheterization in an attempt to close their PDA by transcatheter approach using Amplatzer duct occluder device.
RESULTS
The patient's age ranged from 4 months to 45 years (median 5 years). Successful PDA closure was achieved in 136 patients (91.2%) with 100% complete closure rate within 24 hours after the procedure. Thirteen patients (8.7%) had unsuccessful attempts, 11 (7.3%) of them had failure of deployment of the device, while embolization of the device occurred in two of the patients (1.3%).
CONCLUSIONS
Amplatzer duct occluder device is safe and effective for closure of different types and sizes of PDA with low rate of complication.
背景
动脉导管未闭（PDA）是先天性心脏病的常见形式，约占先天性心脏病的5% - 10%。手术闭合安全有效；然而，某些患者可能会出现一些并发症。最近，使用Amplatzer动脉导管封堵器经导管闭合PDA已被证明是安全有效的。
目的
评估使用该装置经导管闭合PDA是否可作为手术闭合的替代方法。
患者与方法
2006年7月至2008年7月期间，149例PDA患者（98例女性，51例男性）接受了心导管检查，试图使用Amplatzer动脉导管封堵器经导管闭合其PDA。
结果
患者年龄范围为4个月至45岁（中位年龄5岁）。136例患者（91.2%）成功闭合PDA，术后24小时内完全闭合率达100%。13例患者（8.7%）尝试失败，其中11例（7.3%）封堵器植入失败，2例患者（1.3%）出现封堵器栓塞。
结论
Amplatzer动脉导管封堵器对于不同类型和大小的PDA闭合安全有效，并发症发生率低。
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