Lama Moré R, Prieto Bozano G, Carrasco Gandía S, Miralles Adarraga T, Polanco Allúe I
Unidad de Gastroenterología y Nutrición, Hospital Infantil La Paz, Madrid.
An Esp Pediatr. 1990 Aug;33(2):113-6.
We report a retrospective review of primary peptic ulcer peptic disease in 61 children. The follow-up period ranged from 1 month to 6 years. All cases were confirmed by endoscopic examination and related with radiological studies result. The number of ulcer peptic disease detected increased as much as the number of endoscopies were performed annually. In the last 20 patients pinch biopsies from antrum were taken looking for Campylobacter pylori, encountering 10 positives. The relation male:female were 2:1. Gastrointestinal bleeding had occurred in children below 6 years and abdominal pain was seen in older children. All of patients who had C. pylory infection had had recurrent abdominal pain. Three peptic ulcer were documented in patients with cystic fibrosis, which had the worse response to medical treatment. Others, had a satisfactory response.
我们报告了对61例儿童原发性消化性溃疡疾病的回顾性研究。随访期为1个月至6年。所有病例均经内镜检查确诊,并与放射学研究结果相关。每年进行的内镜检查数量增加,检测到的消化性溃疡疾病数量也相应增加。在最后20例患者中,取胃窦部钳取活检以寻找幽门螺杆菌,发现10例阳性。男女比例为2:1。6岁以下儿童出现胃肠道出血,年龄较大的儿童出现腹痛。所有幽门螺杆菌感染的患者都有反复腹痛。囊性纤维化患者中有3例记录有消化性溃疡,其对药物治疗的反应较差。其他患者反应良好。