Rahatullah Arsalan, Waheed Zeeshan, Khan Javaid A
Section of Pulmonary & Critical Care Medicine, Department of Medicine, The Aga Khan University Hospital, Karachi.
J Pak Med Assoc. 2012 May;62(5):493-5.
Pulmonary hyalinising granulomas are rare, noninfectious fibrosclerosing lesions of the lung which can mimic metastatic disease. It was first described in literature by Engleman et al in the year 1977. Its etiology is unknown but they may be caused by an exaggerated immune response. The patient typically presents with cough, chest pain. dyspnoea or haemoptysis in association with multiple bilateral parenchymal nodules. We report the case of a 20 years old male who presented with a 12-month history of worsening dry cough. His plain chest radiograph and subsequent CT scan revealed bilateral pulmonary nodules. A CT guided biopsy of the pulmonary lesions was consistent with Pulmonary Hyalinising Granuloma [PHG].
肺透明变性肉芽肿是一种罕见的、非感染性的肺纤维硬化性病变，可酷似转移性疾病。1977年Engleman等人首次在文献中对其进行描述。其病因不明，但可能由过度的免疫反应引起。患者通常表现为咳嗽、胸痛、呼吸困难或咯血，并伴有双侧多个肺实质结节。我们报告一例20岁男性患者，有12个月干咳加重病史。其胸部X线平片及随后的CT扫描显示双侧肺结节。肺部病变的CT引导下活检结果符合肺透明变性肉芽肿（PHG）。
