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玫瑰果——一种治疗炎症和关节炎的循证草药。

Rosehip - an evidence based herbal medicine for inflammation and arthritis.

作者信息

Cohen Marc

机构信息

School of Health Sciences, RMIT University, Victoria.

出版信息

Aust Fam Physician. 2012 Jul;41(7):495-8.

Abstract

BACKGROUND

Rosehips - which contain a particular type of galactolipid - have a specific antiinflammatory action. A standardised rosehip powder has been developed to maximise the retention of phytochemicals. This powder has demonstrated antioxidant and anti-inflammatory activity as well as clinical benefits in conditions such as osteoarthritis, rheumatoid arthritis and inflammatory bowel disease.

OBJECTIVE

To examine the evidence suggesting that standardised rosehip powder may be a viable replacement or supplement for conventional therapies used in inflammatory diseases such as arthritis.

DISCUSSION

A meta-analysis of three randomised controlled trials involving 287 patients with a median treatment period of 3 months reported that treatment with standardised rosehip powder consistently reduced pain scores and that patients allocated to rosehip powder were twice as likely to respond to rosehip compared to placebo. In contrast to nonsteroidal anti-inflammatory drugs and aspirin, rosehip has antiinflammatory actions that do not have ulcerogenic effects and do not inhibit platelets nor influence the coagulation cascade or fibrinolysis.

摘要

背景

玫瑰果含有一种特殊类型的半乳糖脂,具有特定的抗炎作用。已开发出一种标准化的玫瑰果粉,以最大程度保留植物化学物质。这种粉末已证明具有抗氧化和抗炎活性,并且在骨关节炎、类风湿性关节炎和炎症性肠病等病症中具有临床益处。

目的

研究表明标准化玫瑰果粉可能是关节炎等炎症性疾病中传统疗法的可行替代或补充疗法的证据。

讨论

一项对三项随机对照试验的荟萃分析涉及287名患者,中位治疗期为3个月,报告称标准化玫瑰果粉治疗持续降低疼痛评分,且分配到玫瑰果粉组的患者对玫瑰果产生反应的可能性是安慰剂组的两倍。与非甾体抗炎药和阿司匹林不同,玫瑰果具有抗炎作用,不会产生致溃疡作用,不会抑制血小板,也不会影响凝血级联反应或纤维蛋白溶解。

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