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农村和偏远地区年轻澳大利亚原住民 2 型糖尿病:诊断、筛查、管理和预防。

Type 2 diabetes in young Indigenous Australians in rural and remote areas: diagnosis, screening, management and prevention.

机构信息

Baker IDI Central Australia, Alice Springs, NT.

出版信息

Med J Aust. 2012 Jul 2;197(1):32-6. doi: 10.5694/mja12.10036.

DOI:10.5694/mja12.10036
PMID:22762229
Abstract

The burden of type 2 diabetes mellitus (T2DM) among Indigenous children and adolescents is much greater than in non-Indigenous young people and appears to be rising, although data on epidemiology and complications are limited. Young Indigenous people living in remote areas appear to be at excess risk of T2DM. Most young Indigenous people with T2DM are asymptomatic at diagnosis and typically have a family history of T2DM, are overweight or obese and may have signs of hyperinsulinism such as acanthosis nigricans. Onset is usually during early adolescence. Barriers to addressing T2DM in young Indigenous people living in rural and remote settings relate to health service access, demographics, socioeconomic factors, cultural factors, and limited resources at individual and health service levels. We recommend screening for T2DM for any Aboriginal or Torres Strait Islander person aged > 10 years (or past the onset of puberty) who is overweight or obese, has a positive family history of diabetes, has signs of insulin resistance, has dyslipidaemia, has received psychotropic therapy, or has been exposed to diabetes in utero. Individualised management plans should include identification of risk factors, complications, behavioural factors and treatment targets, and should take into account psychosocial factors which may influence health care interaction, treatment success and clinical outcomes. Preventive strategies, including lifestyle modification, need to play a dominant role in tackling T2DM in young Indigenous people.

摘要

2 型糖尿病(T2DM)在土著儿童和青少年中的负担比非土著年轻人重得多,而且似乎还在上升,尽管有关流行病学和并发症的数据有限。居住在偏远地区的年轻土著人似乎面临着更高的 T2DM 风险。大多数被诊断患有 T2DM 的年轻土著人在诊断时没有症状,通常有 T2DM 的家族史,超重或肥胖,并且可能有黑棘皮病等胰岛素抵抗的迹象。发病通常在青春期早期。在农村和偏远地区的年轻土著人中,解决 T2DM 的障碍与卫生服务的获取、人口统计学、社会经济因素、文化因素以及个人和卫生服务层面的有限资源有关。我们建议对任何年龄> 10 岁(或青春期后)的超重或肥胖的土著或托雷斯海峡岛民、有糖尿病阳性家族史、有胰岛素抵抗迹象、有血脂异常、接受过精神治疗或有宫内接触糖尿病的人进行 T2DM 筛查。个体化管理计划应包括识别风险因素、并发症、行为因素和治疗目标,并应考虑可能影响医疗保健互动、治疗成功和临床结果的社会心理因素。预防策略,包括生活方式的改变,需要在解决年轻土著人中的 T2DM 中发挥主导作用。

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