Department of Anaesthesiology and Intensive Care, Central Hospital of Sogn og Fjordane, Førde, Norway.
Acta Anaesthesiol Scand. 2012 Sep;56(8):1066-8. doi: 10.1111/j.1399-6576.2012.02732.x. Epub 2012 Jul 4.
We report a patient with severe anaphylactic shock immediately after injection of i.v. fluorescein. The patient recovered without sequela. Immunoglobulin E (IgE) mechanism was highly suggestive with significant increase in serum tryptase, positive basophil allergen threshold sensitivity (CD-sens) and histamine release tests towards fluorescein. This is, to our knowledge, the first report where CD-sens has been used to aid in diagnosing an IgE-mediated anaphylactic shock caused by fluorescein.
我们报告了一例静脉注射荧光素后立即发生严重过敏性休克的患者。患者无后遗症恢复。免疫球蛋白 E（IgE）机制高度提示血清类胰蛋白酶显著增加，对荧光素的嗜碱性粒细胞过敏原阈值敏感性（CD-sens）和组胺释放试验呈阳性。据我们所知，这是首次使用 CD-sens 协助诊断由荧光素引起的 IgE 介导的过敏性休克的报告。
