Frohlich M W, Miller P L, Morrow J S
Harvard Medical School, Boston, Massachusetts 02138.
Comput Biomed Res. 1990 Dec;23(6):499-513. doi: 10.1016/0010-4809(90)90037-d.
PATHMASTER is an expert system under development to assist in teaching histopathologic differential diagnosis. The system incorporates two "orthogonal" representations of the knowledge required to perform differential diagnosis. One representation groups histopathologic features around the anatomic structures of liver tissue, the second representation groups the features around the diseases in which they occur. Using these two representations, PATHMASTER models the process of diagnosis as a "dynamic competition" between systematic analysis and disease-directed deduction. By varying two parameters of PATHMASTER's underlying mathematical model, the interplay between these factors can be varied.
PATHMASTER是一个正在开发的专家系统，旨在辅助组织病理学鉴别诊断教学。该系统结合了进行鉴别诊断所需知识的两种“正交”表示。一种表示围绕肝组织的解剖结构对组织病理学特征进行分组，第二种表示围绕出现这些特征的疾病对特征进行分组。利用这两种表示，PATHMASTER将诊断过程建模为系统分析和疾病导向推理之间的“动态竞争”。通过改变PATHMASTER基础数学模型的两个参数，可以改变这些因素之间的相互作用。
