Tompson Anna J, Peterson Gregory M, Jackson Shane L, Hughes Jeffrey D, Raymond Kenneth
Tasmanian School of Pharmacy, University of Tasmania, Hobart.
Int J Clin Pharmacol Ther. 2012 Sep;50(9):639-46. doi: 10.5414/CP201720.
To identify and resolve discrepancies in admission medication histories, utilizing community pharmacy dispensing data, in newly hospitalized patients and investigate the relationship between unresolved discrepancies and length of hospital stay.
Eligible patients (2 or more chronic conditions, 3 or more chronic medications and aged over 50 years) were randomized to the intervention or control group. Within 24 h of admission, the patient's nominated community pharmacy was contacted, a 6-month dispensing history obtained, patient was interviewed and a current medication list compiled. This was compared with the hospital drug chart. Discrepancies for the intervention group were discussed with the attending doctor. Subsequent resolution of discrepancies was assessed for all patients.
487 patients were included (203 intervention, 284 control). Approximately 66% of all patients had at least 1 discrepancy between their reconciled list of medications and their initial drug chart, with no significant difference between the groups. Significantly more intervention patients had at least 1 discrepancy resolved in the first 48 h than control patients (intervention 78.1%; control 36.5%; p < 0.0001). A weak correlation was found between the number of discrepancies not acted on and length of hospital stay (Spearman Rho = 0.1, n = 487, p < 0.01).
Errors in admission medication histories are common and potentially lead to an increased length of stay. The provision of a 6-month community pharmacy dispensing history at the time of hospital admission is an important addition to ensure an accurate medication chart is compiled.
利用社区药房配药数据,识别并解决新入院患者入院用药史中的差异,并调查未解决差异与住院时间之间的关系。
符合条件的患者(患有2种或更多慢性疾病、服用3种或更多慢性药物且年龄超过50岁)被随机分为干预组或对照组。入院后24小时内,联系患者指定的社区药房,获取6个月的配药史,对患者进行访谈并编制当前用药清单。将其与医院药物图表进行比较。干预组的差异与主治医生进行讨论。对所有患者差异的后续解决情况进行评估。
共纳入487例患者(203例干预组,284例对照组)。所有患者中约66%的用药调和清单与初始药物图表之间至少存在1处差异,两组之间无显著差异。在最初48小时内,干预组中至少有1处差异得到解决的患者明显多于对照组(干预组为78.1%;对照组为36.5%;p<0.0001)。未处理的差异数量与住院时间之间存在弱相关性(Spearman Rho=0.1,n=487,p<0.01)。
入院用药史中的错误很常见,可能导致住院时间延长。入院时提供6个月的社区药房配药史是确保编制准确药物图表的一项重要补充。