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[人肺癌组织中含锰超氧化物歧化酶活性]

[Manganese-containing superoxide dismutase activity in human lung cancer tissue].

作者信息

Jiang C G

机构信息

General Hospital of PLA.

出版信息

Zhonghua Zhong Liu Za Zhi. 1990 Sep;12(5):348-50.

PMID:2276325
Abstract

Manganese-containing superoxide dismutase (Mn-SOD) activity in lung cancer tissue from 5 lung cancer patients was measured by nitrite formation method, and lipid peroxide (LPO) was measured spectrophotometrically by thiobarbituric acid reaction. The results showed that Mn-SOD activity was highest in lung cancer tissue, peripheral tissues surrounding the lung cancer stood next and it was lowest in the peripheral normal lung tissue (P less than 0.01). However, LPO value was found to be lower in lung cancer tissues than that in the peripheral normal lung tissues.

摘要

采用亚硝酸盐形成法测定了5例肺癌患者肺癌组织中含锰超氧化物歧化酶(Mn-SOD)的活性,并用硫代巴比妥酸反应分光光度法测定了脂质过氧化物(LPO)。结果显示,肺癌组织中Mn-SOD活性最高,肺癌周围的外周组织次之,外周正常肺组织中最低(P<0.01)。然而,发现肺癌组织中的LPO值低于外周正常肺组织中的LPO值。

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