Disease Early Warning System, Afghan Public Health Institute, Ministry of Public Health, Kabul, Afghanistan.
East Mediterr Health J. 2012 May;18(5):522-6. doi: 10.26719/2012.18.5.522.
Crimean-Congo haemorrhagic fever (CCHF) is a life-threatening viral haemorrhagic fever. This paper reports on the first multifocal outbreak recorded in the Afghanistan. The outbreak was detected in 2008 in the Western Region of the country and 30 cases (17 males and 13 females) were detected between 10 July and 22 October 2008. Standard case definitions based on World Health Organization sources were used. Most of the cases (27) occurred in Herat province; 25 were aged between 18-55, 1 was > 55 years and 4 were 12-18 years (median age was 27 years). The case fatality rate was 33%; 41% among males and 23% among females (P = 0.29). Significantly more patients infected by contact with meat and body fluids died that those whose contact was through animal husbandry or ticks (P = 0.0048). Of the 30 cases, 33 close contacts were traced; 3 were positive for CCHF IgM with no symptomatic evidence of the disease.
克里米亚-刚果出血热（CCHF）是一种危及生命的病毒性出血热。本文报告了阿富汗首例记录的多发性暴发。该暴发于 2008 年在该国西部地区发现，2008 年 7 月 10 日至 10 月 22 日期间共发现 30 例病例（17 名男性和 13 名女性）。使用了基于世界卫生组织来源的标准病例定义。大多数病例（27 例）发生在赫拉特省；25 例年龄在 18-55 岁之间，1 例年龄大于 55 岁，4 例年龄在 12-18 岁之间（中位数年龄为 27 岁）。病死率为 33%；男性为 41%，女性为 23%（P = 0.29）。与接触肉类和体液有关的感染患者的死亡率明显高于与畜牧业或蜱虫有关的患者（P = 0.0048）。在 30 例病例中，追踪到 33 名密切接触者；3 名对 CCHF IgM 呈阳性，没有该疾病的症状证据。
