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验证认知正常老年人的面孔名字联想记忆测验。

Validation of the Face Name Associative Memory Exam in cognitively normal older individuals.

机构信息

Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA.

出版信息

J Clin Exp Neuropsychol. 2012;34(6):580-7. doi: 10.1080/13803395.2012.666230. Epub 2012 Mar 9.

Abstract

The recently developed Face Name Associative Memory Exam (FNAME), a challenging paired associative learning task, shows promise in detecting the subtle cognitive changes characteristic of preclinical Alzheimer's disease. In this study, we evaluated the validity and reliability of the FNAME in 210 cognitively normal older individuals (58-90 years of age). Construct validity of the measure was assessed by principal components analysis, which revealed two independent factors. Correlations between the FNAME subtests and another episodic memory test were significant. The results indicated strong test-retest reliability in a subsample (n = 41). Normative data stratified by age were also generated.

摘要

最近开发的面孔名称联想记忆测验(FNAME)是一项具有挑战性的成对联想学习任务,有望检测出临床前阿尔茨海默病特征的微妙认知变化。在这项研究中,我们评估了 FNAME 在 210 名认知正常的老年人(58-90 岁)中的有效性和可靠性。通过主成分分析评估了该测量的构念效度,结果显示了两个独立的因素。FNAME 子测验与另一种情景记忆测验之间的相关性显著。结果表明,在一个亚样本(n = 41)中具有很强的测试重测信度。还生成了按年龄分层的规范数据。

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