Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
Psychiatry Res. 2012 Dec 30;200(2-3):1044-6. doi: 10.1016/j.psychres.2012.06.001. Epub 2012 Jul 4.
We report the results of a high-density attempted suicide association study of the X chromosome, which genotyped 23,141 SNPs on 983 attempters and 1143 non-attempters and generated modest evidence for association for SH3KBP1 (P=1.07×10(-4)) and GRIA3 (P=4.01×10(-4)). These findings highlight the need for larger sample sets and meta-analytic approaches.
我们报告了一项针对 X 染色体的高密度自杀未遂关联研究结果，该研究对 983 名自杀未遂者和 1143 名非自杀未遂者进行了 23,141 个单核苷酸多态性（SNP）的基因分型，并为 SH3KBP1（P=1.07×10(-4))和 GRIA3（P=4.01×10(-4))的关联提供了适度的证据。这些发现突出表明需要更大的样本集和荟萃分析方法。
