真菌溶血素。
Fungal hemolysins.
机构信息
Allergy and Clinical Immunology Branch, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA.
出版信息
Med Mycol. 2013 Jan;51(1):1-16. doi: 10.3109/13693786.2012.698025. Epub 2012 Jul 9.
Abstract
Hemolysins are a class of proteins defined by their ability to lyse red cells but have been described to exhibit pleiotropic functions. These proteins have been extensively studied in bacteria and more recently in fungi. Within the last decade, a number of studies have characterized fungal hemolysins and revealed a fascinating yet diverse group of proteins. The purpose of this review is to provide a synopsis of the known fungal hemolysins with an emphasis on those belonging to the aegerolysin protein family. New insight and perspective into fungal hemolysins in biotechnology and health are additionally presented.
摘要
溶血素有溶解红细胞的能力，根据这一特性将其定义为一类蛋白质，但现已发现其具有多种功能。这些蛋白质在细菌中已有广泛研究，最近在真菌中也有研究。在过去十年中，许多研究已经对真菌溶血素有了特征描述，揭示了一组令人着迷但又多样化的蛋白质。本文综述了已知的真菌溶血素，重点介绍了属于蜂斗菜毒素蛋白家族的溶血素。本文还进一步介绍了真菌溶血素在生物技术和健康领域的新见解和新视角。
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