The kapurimycins, new antitumor antibiotics produced by Streptomyces. Physico-chemical properties and structure determination.
作者信息
Yoshida M, Hara M, Saitoh Y, Sano H
机构信息
Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.
出版信息
J Antibiot (Tokyo). 1990 Dec;43(12):1519-23. doi: 10.7164/antibiotics.43.1519.
PMID:2276971
Abstract
The kapurimycins A1, A2 and A3 were revealed to be new antitumor antibiotics with molecular formula of C27H26O9, C26H24O9 and C27H24O9, respectively. The structures of the kapurimycins were determined by NMR spectroscopic analysis. The kapurimycins are new class of polycyclic microbial metabolites having the tetrahydroanthra-gamma-pyrone skeleton and the beta, gamma-unsaturated delta-keto carboxylic acid structure. The individual components of the kapurimycins differ from one another in the side chain at the pyrone ring of the molecule.
摘要
Zotero 插件