Arribas M P, Soro P, Silvestre J F
Departamento de Dermatología, Hospital General Universitario de Alicante, España.
Actas Dermosifiliogr. 2013 Jan;104(1):29-37. doi: 10.1016/j.ad.2012.03.005. Epub 2012 Jul 4.
Allergic contact dermatitis due to fragrances usually manifests as subacute or chronic dermatitis because fragrances are found in a wide range of products to which patients are repeatedly exposed. The typical patient is a middle-aged woman with dermatitis on her hands and face, although other sites may be affected depending on the allergen and the product in which it is found. The standard patch test series of the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) contains 4 fragrance markers: balsam of Peru, fragrance mix i, fragrance mix ii, and lyral. Testing with a specific fragrance series is recommended in patients with a positive result to any of these 4 markers. The use of a specific fragrance series and new legislation obliging manufacturers to specify the fragrances used in their products, will help to improve the management of allergic contact dermatitis due to fragrances.
由于香料引起的过敏性接触性皮炎通常表现为亚急性或慢性皮炎，因为香料存在于患者反复接触的多种产品中。典型患者是一名中年女性，手部和面部患有皮炎，不过根据变应原及其所在产品的不同，身体其他部位也可能受到影响。西班牙接触性皮炎和皮肤过敏研究小组（GEIDAC）的标准斑贴试验系列包含4种香料标记物：秘鲁香脂、香料混合物I、香料混合物II和lyral。对这4种标记物中任何一种检测结果呈阳性的患者，建议使用特定香料系列进行检测。使用特定香料系列以及要求制造商在其产品中明确所使用香料的新法规，将有助于改善因香料引起的过敏性接触性皮炎的管理。
