注射用氨基糖苷类药物（庆大霉素、妥布霉素、奈替米星、阿米卡星）合理应用的最新进展。药理特性、适应证、剂量、给药方式及治疗监测。 - Suppr

Suppr

超能文献

Update on good use of injectable aminoglycosides, gentamycin, tobramycin, netilmycin, amikacin. Pharmacological properties, indications, dosage, and mode of administration, treatment monitoring.

出版信息

Med Mal Infect. 2012 Jul;42(7):301-8. doi: 10.1016/j.medmal.2011.07.007. Epub 2012 Jul 7.

DOI:10.1016/j.medmal.2011.07.007

PMID:22770656

Abstract

摘要

相似文献

Update on good use of injectable aminoglycosides, gentamycin, tobramycin, netilmycin, amikacin. Pharmacological properties, indications, dosage, and mode of administration, treatment monitoring.注射用氨基糖苷类药物（庆大霉素、妥布霉素、奈替米星、阿米卡星）合理应用的最新进展。药理特性、适应证、剂量、给药方式及治疗监测。

Med Mal Infect. 2012 Jul;42(7):301-8. doi: 10.1016/j.medmal.2011.07.007. Epub 2012 Jul 7.

The aminoglycosides. Streptomycin, kanamycin, gentamicin, tobramycin, amikacin, netilmicin, sisomicin.氨基糖苷类抗生素。链霉素、卡那霉素、庆大霉素、妥布霉素、阿米卡星、奈替米星、西索米星。

Mayo Clin Proc. 1983 Feb;58(2):99-102.

A survey of prospective, controlled clinical trials of gentamicin, tobramycin, amikacin, and netilmicin.一项关于庆大霉素、妥布霉素、阿米卡星和奈替米星的前瞻性对照临床试验的调查。

Clin Ther. 1982;5(2):155-62.

Epidemiology of resistance to netilmicin and other aminoglycosides.奈替米星及其他氨基糖苷类抗生素耐药性的流行病学

Chemioterapia. 1986 Jun;5(3):191-5.

Comparative studies of intermittent and continuous administration of aminoglycosides in the treatment of bronchopulmonary infections due to gram-negative bacteria.氨基糖苷类药物间歇性与持续性给药治疗革兰氏阴性菌所致支气管肺部感染的对比研究。

Rev Infect Dis. 1981 Jan-Feb;3(1):74-83. doi: 10.1093/clinids/3.1.74.

Incorporation, release and in-vitro antibacterial activity of liposomal aminoglycosides against Pseudomonas aeruginosa.脂质体氨基糖苷类药物对铜绿假单胞菌的包封、释放及体外抗菌活性

J Antimicrob Chemother. 1995 Oct;36(4):631-9. doi: 10.1093/jac/36.4.631.

New developments in antimicrobial therapy.

Del Med J. 1978 Jan;50(1):33-8.

Therapeutic drug monitoring of aminoglycosides in acute myeloid leukaemia patients.急性髓系白血病患者氨基糖苷类药物的治疗药物监测

Scand J Infect Dis. 2012 May;44(5):398-401. doi: 10.3109/00365548.2011.645868. Epub 2012 Jan 11.

[The clinical view of aminoglycoside antibiotics].

Adv Clin Pharmacol. 1978;15:119-26.

Surveillance of aminoglycoside resistance. European data.氨基糖苷类耐药性监测。欧洲数据。

Am J Med. 1986 Jun 30;80(6B):76-81. doi: 10.1016/0002-9343(86)90483-3.

引用本文的文献

Amikacin Dosing Adjustment in Critically Ill Oncologic Patients: A Study with Real-World Patients, PBPK Analysis, and Digital Twins.危重症肿瘤患者的阿米卡星剂量调整：一项针对真实世界患者、PBPK分析和数字孪生的研究。

Pharmaceutics. 2025 Feb 24;17(3):297. doi: 10.3390/pharmaceutics17030297.

Amikacin use in critically ill patients requiring renal replacement therapy: the AMIDIAL-ICU study.在需要肾脏替代治疗的危重症患者中使用阿米卡星：AMIDIAL-ICU研究

Ann Intensive Care. 2025 Mar 26;15(1):42. doi: 10.1186/s13613-025-01461-z.

Pragmatic physiologically-based pharmacokinetic modeling to support clinical implementation of optimized gentamicin dosing in term neonates and infants: proof-of-concept.基于生理学的实用药代动力学建模，以支持足月儿和婴儿优化庆大霉素给药方案的临床实施：概念验证

Front Pediatr. 2023 Nov 21;11:1288376. doi: 10.3389/fped.2023.1288376. eCollection 2023.

What is the right gentamicin dose for multiple trauma patients? A Monte Carlo simulation exploration study.对于多发伤患者，庆大霉素的合适剂量是多少？一项蒙特卡洛模拟探索性研究。

Int J Crit Illn Inj Sci. 2023 Jul-Sep;13(3):118-124. doi: 10.4103/ijciis.ijciis_14_23. Epub 2023 Sep 21.

Recommendations of Gentamicin Dose Based on Different Pharmacokinetic/Pharmacodynamic Targets for Intensive Care Adult Patients: A Redefining Approach.基于不同药代动力学/药效学靶点的成人重症监护患者庆大霉素剂量推荐：一种重新定义的方法

Clin Pharmacol. 2023 Jul 4;15:67-76. doi: 10.2147/CPAA.S417298. eCollection 2023.

Development of a Predictive Dosing Nomogram to Achieve PK/PD Targets of Amikacin Initial Dose in Critically Ill Patients: A Non-Parametric Approach.开发预测性给药列线图以实现重症患者阿米卡星初始剂量的药代动力学/药效学目标：一种非参数方法。

Antibiotics (Basel). 2023 Jan 9;12(1):123. doi: 10.3390/antibiotics12010123.

Implementation of Model-Based Dose Adjustment of Tobramycin in Adult Patients with Cystic Fibrosis.基于模型的妥布霉素剂量调整在成年囊性纤维化患者中的应用

Pharmaceutics. 2022 Aug 22;14(8):1750. doi: 10.3390/pharmaceutics14081750.

Evaluation of amikacin dosing schedule in critically ill elderly patients with different stages of renal dysfunction.评价不同肾功能阶段危重症老年患者阿米卡星的给药方案。

Eur J Hosp Pharm. 2022 Mar;29(e1):e67-e71. doi: 10.1136/ejhpharm-2021-002986. Epub 2021 Sep 29.

An international survey on aminoglycoside practices in critically ill patients: the AMINO III study.一项关于危重症患者氨基糖苷类药物使用情况的国际调查：AMINO III研究。

Ann Intensive Care. 2021 Mar 19;11(1):49. doi: 10.1186/s13613-021-00834-4.

Population Pharmacokinetic Study of the Suitability of Standard Dosing Regimens of Amikacin in Critically Ill Patients with Open-Abdomen and Negative-Pressure Wound Therapy.一项关于开腹合并负压伤口治疗的危重症患者中应用标准剂量阿米卡星的适用性的群体药代动力学研究。

Antimicrob Agents Chemother. 2020 Mar 24;64(4). doi: 10.1128/AAC.02098-19.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验