Cone L A
Clin Ther. 1982;5(2):155-62.
Data from 24 prospective, controlled clinical studies of the aminoglycosides gentamicin, tobramycin, amikacin, and netilmicin are reviewed. According to these findings, netilmicin is the safest and most effective of the four types (P less than 0.01, both comparisons), and gentamicin is more effective than tobramycin (P less than 0.05) and less ototoxic than amikacin (P less than 0.05).
对庆大霉素、妥布霉素、阿米卡星和奈替米星这四种氨基糖苷类药物的24项前瞻性对照临床研究数据进行了综述。根据这些研究结果，奈替米星是这四种类型中最安全、最有效的（两项比较P均小于0.01），庆大霉素比妥布霉素更有效（P小于0.05），且耳毒性比阿米卡星小（P小于0.05）。
