抵抗促进糖尿病的生活方式因素——其机制是什么？
Resistance to diabetes-promoting lifestyle factors -- what is the mechanism?
机构信息
Immunobiology Research Group, Institute of Molecular Medicine, University of Düsseldorf, D-4001 Düsseldorf, Germany.
出版信息
Diabetes Res Clin Pract. 2012 Aug;97(2):172-4. doi: 10.1016/j.diabres.2012.06.006. Epub 2012 Jul 5.
Abstract
Not all people exposed to diabetes-promoting lifestyle factors progress to overt type 2 diabetes. The emerging concept of hormesis provides an explanation for the resistance to metabolic stress. Hormesis requires limited stress or damage which elicits an adaptive repair and protective response which renders the organism resistant to further metabolic stress.
摘要
并非所有接触到促进糖尿病发生的生活方式因素的人都会进展为显性 2 型糖尿病。应激适应的新兴概念为此提供了代谢应激抵抗的解释。应激适应需要有限的应激或损伤，从而引发适应性修复和保护反应，使机体能够抵抗进一步的代谢应激。
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