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Frequency of complications and usefulness of the minor salivary gland biopsy.

作者信息

Lida Santiago María, Seisdedos María Renata, García Salinas Rodrigo Nicolás, Secco Anastasia, Marino Claverie Lucila, Techera Lorena, Takashima Lorena, Aicardi Pedro, Sandi Rosales Marco Antonio, Knobel Elizabeth, Magri Sebastián Juan, Catalán Pellet Antonio Carlos

机构信息

Servicio de Reumatología, Hospital Bernardino Rivadavia, Ciudad Autónoma de Buenos Aires, Argentina.

出版信息

Reumatol Clin. 2012 Sep-Oct;8(5):255-8. doi: 10.1016/j.reuma.2012.03.006. Epub 2012 Jul 6.

DOI:10.1016/j.reuma.2012.03.006
PMID:22771273
Abstract

UNLABELLED

Findings of specific antibodies and histopathology data are essential for the diagnosis of Sjögren syndrome (SS). Although the minor salivary gland biopsy (MSGB) is technically simple, it needs to be performed in a medical institution to avoid complications.

OBJECTIVE

To determine the frequency of complications and the usefulness of this technique.

MATERIALS AND METHODS

Patients who underwent a minor salivary gland biopsy for a possible diagnosis of SS at Rivadavia Hospital between October 2007 and May 2010 where included. The patients were seen a week and a month after the procedure for follow up.

RESULTS

Frequency of acute complications (n=186): 15 patients; 8.1%, 95% CI: 4.7-13.2 (Bleeding 7.5%, syncope 3.2%, hematoma 2.7%. No accidents occurred). Medium term complications (n=164): 16 patients: 9.75%, 95% CI: 5.9-15.6 (pain 7.32%, inflammation 3.66%, sensitivity disorders 3.05%, granuloma 1.22%,). No infections or suture dehiscence occurred. Microscopic results: 154 biopsy reports were received: glandular 90.9%, 95% CI: 85-95 (typical, sialadenitis, grade III and IV infiltration).

CONCLUSIONS

MSGB has very low frequency of medium term and acute complications and it has high usefulness.

摘要

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