Tanaka K, Mihara M, Shimao S, Taniguchi K
Department of Dermatology, Tottori University School of Medicine, Yonago, Japan.
J Dermatol. 1990 Sep;17(9):575-80. doi: 10.1111/j.1346-8138.1990.tb01698.x.
A seventeen-month-old female had a pigmented nodule on her left lower leg. The excised lesion was histologically diagnosed as a Spitz nevus, composed mainly of spindle-shaped melanocytes containing large amounts of melanin pigment. When nodular regrowth was seen at the operative site, the recurrent lesion was radically excised as nodular melanoma. However the histological characteristics of the second excised specimen were essentially the same as those in the initially excised one except for the existence of the newly formed collagen fibers, which may suggest an involuting stage in the central portion of the lesion.
一名17个月大的女性左小腿有一个色素性结节。切除的病变经组织学诊断为斯皮茨痣，主要由含有大量黑色素的梭形黑素细胞组成。当手术部位出现结节性复发时，将复发病变作为结节性黑色素瘤进行根治性切除。然而，除了新形成的胶原纤维外，第二次切除标本的组织学特征与最初切除的标本基本相同，这可能提示病变中央部分处于退化阶段。
