Antoine J M, Gomes A, Uzan S, Alvarez S, Cornet D, Tibi C, Mandelbaum J, Plachot M, Salat-Barroux J
Service de Gynécologie-Obstétrique, Hôpital Tenon, Paris.
J Gynecol Obstet Biol Reprod (Paris). 1990;19(7):901-7.
The obstetrical outcome of 305 pregnancies obtained by in vitro fertilization were reviewed: out of 275 pregnancies following fresh embryo transfers, 205 (74.5%) were single, 64 (23.3%) double and 6 (2.2%) triple). We observed increased frequencies of high blood pressure linked to older maternal age, bleeding in the late pregnancy and breech presentation, which could be associated to abnormal insertion of umbilical cord and/or placenta. Multiple pregnancies, especially the triple ones, are of the highest risk (intra-uterine growth retardation, low birth weight). Nevertheless the total fetal mortality remains low in our experience. Data about 22 pregnancies following cryopreserved embryo transfer, 5 after oocyte donation and 3 therapeutic abortions are also given.
回顾了305例体外受精妊娠的产科结局：在275例新鲜胚胎移植后的妊娠中，205例（74.5%）为单胎，64例（23.3%）为双胎，6例（2.2%）为三胎。我们观察到，与高龄产妇相关的高血压、妊娠晚期出血和臀位的发生率增加，这可能与脐带和/或胎盘异常植入有关。多胎妊娠，尤其是三胎妊娠，风险最高（宫内生长迟缓、低出生体重）。然而，根据我们的经验，总胎儿死亡率仍然较低。还给出了22例冷冻胚胎移植后妊娠、5例卵母细胞捐赠后妊娠和3例治疗性流产的数据。
