钯催化[60]富勒烯与 N-苄基磺酰胺的杂芳环化反应及后续官能化。

Palladium-catalysed heteroannulation of [60]fullerene with N-benzyl sulfonamides and subsequent functionalisation.

机构信息

Hefei National Laboratory for Physical Sciences at Microscale, and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, PR China.

出版信息

Chem Commun (Camb). 2012 Aug 21;48(65):8132-4. doi: 10.1039/c2cc33923d. Epub 2012 Jul 9.

DOI:10.1039/c2cc33923d

PMID:22773035

Abstract

The palladium-catalysed heteroannulation of [60]fullerene with various N-benzyl sulfonamides via C-H bond activation affords [60]fullerene-fused tetrahydroisoquinolines. In the presence of a Brønsted acid [60]fullerene-fused tetrahydroisoquinolines are transformed to [60]fullerene-fused indanes, in which the sulfonamide group can be removed or replaced with an aryl group.

摘要

钯催化的[60]富勒烯与各种 N-苄基磺酰胺通过 C-H 键活化的杂芳环化反应，得到[60]富勒烯稠合的四氢异喹啉。在布朗斯台德酸的存在下，[60]富勒烯稠合的四氢异喹啉可以转化为[60]富勒烯稠合的茚满，其中磺酰胺基可以被去除或被芳基取代。