Inagaki Keiji, Iseda Ayumi, Ohkoshi Kishiko
Department of Ophthalmology, St. Luke's International Hospital, Tokyo, Japan.
Nippon Ganka Gakkai Zasshi. 2012 Jun;116(6):568-74.
To investigate the efficacy of subthreshold micropulse diode laser photocoagulation (SMDLP) combined with direct photocoagulation.
Twenty one eyes of 20 patients with diabetic macular edema were treated with SMDLP and direct photocoagulation for microaneurysms within 1 month after SMDLP. The mean visual acuity in logMAR units and central macular thickness (CMT) were evaluated both before and after laser treatment by retrospective chart review and optical coherence tomography (OCT).
The mean visual acuity did not change significantly at 3 and at 6 months. The mean CMT was significantly reduced at 3 and 6 months (3 months: p = 0.018, 6 months: p = 0.004). Visual acuity improved or maintained for 6 months in all of the patients (100%, 20 eyes of 20 patients).
SMDLP combined with direct photocoagulation maintains visual acuity and improves diabetic macular edema for at least 6 months.
探讨阈下微脉冲二极管激光光凝(SMDLP)联合直接光凝的疗效。
20例糖尿病性黄斑水肿患者的21只眼接受了SMDLP治疗,并在SMDLP治疗后1个月内对微动脉瘤进行直接光凝。通过回顾性病历审查和光学相干断层扫描(OCT)评估激光治疗前后的平均对数最小分辨角视力(logMAR)和中心黄斑厚度(CMT)。
3个月和6个月时平均视力无显著变化。3个月和6个月时平均CMT显著降低(3个月:p = 0.018,6个月:p = 0.004)。所有患者(100%,20例患者的20只眼)的视力在6个月内得到改善或维持。
SMDLP联合直接光凝可维持视力并改善糖尿病性黄斑水肿至少6个月。