Vision Performance Institute, Pacific University College of Optometry, Forest Grove, USA.
Ophthalmic Physiol Opt. 2012 Sep;32(5):412-20. doi: 10.1111/j.1475-1313.2012.00922.x. Epub 2012 Jul 7.
To help maintain clear vision and ocular surface health, eye blinks occur to distribute natural tears over the ocular surface, especially the corneal surface. Contact lens wearers may suffer from poor vision and dry eye symptoms due to difficulty in lens surface wetting and reduced tear production. Sustained viewing of a computer screen reduces eye blinks and exacerbates such difficulties. The present study evaluated the wetting effect of lens care solutions (LCSs) on blink rate, dry eye symptoms, and vision performance.
Sixty-five adult habitual soft contact lens wearers were recruited to adapt to different LCSs (Opti-free, ReNu, and ClearCare) in a cross-over design. Blink rate in pictorial viewing and reading (measured with an eyetracker), dry eye symptoms (measured with the Ocular Surface Disease Index questionnaire), and visual discrimination (identifying tumbling E) immediately before and after eye blinks were measured after 2 weeks of adaption to LCS. Repeated measures anova and mixed model ancova were conducted to evaluate effects of LCS on blink rate, symptom score, and discrimination accuracy.
Opti-Free resulted in lower dry eye symptoms (p = 0.018) than ClearCare, and lower spontaneous blink rate (measured in picture viewing) than ClearCare (p = 0.014) and ReNu (p = 0.041). In reading, blink rate was higher for ClearCare compared to ReNu (p = 0.026) and control (p = 0.024). Visual discrimination time was longer for the control (daily disposable lens) than for Opti-Free (p = 0.007), ReNu (p = 0.009), and ClearCare (0.013) immediately before the blink.
LCSs differently affected blink rate, subjective dry eye symptoms, and visual discrimination speed. Those with wetting agents led to significantly fewer eye blinks while affording better ocular comfort for contact lens wearers, compared to that without. LCSs with wetting agents also resulted in better visual performance compared to wearing daily disposable contact lenses. These presumably are because of improved tear film quality.
为了保持清晰的视力和眼部健康，眨眼可以将天然泪液分布在眼部表面，尤其是角膜表面。由于镜片表面湿润困难和泪液产生减少，隐形眼镜佩戴者可能会出现视力不佳和干眼症症状。持续观看电脑屏幕会减少眨眼次数，从而加剧这些困难。本研究评估了隐形眼镜护理液 (LCS) 对眨眼频率、干眼症症状和视力表现的润湿效果。
65 名成年软性隐形眼镜惯常佩戴者采用交叉设计适应不同的 LCS（Opti-free、ReNu 和 ClearCare）。使用眼动追踪仪测量在图片观看和阅读时的眨眼频率，使用眼表疾病指数问卷测量干眼症症状，以及在眨眼前后立即测量视觉辨别力（识别滚动 E）。适应 LCS 两周后测量。采用重复测量方差分析和混合模型协方差分析评估 LCS 对眨眼频率、症状评分和辨别准确性的影响。
Opti-Free 比 ClearCare 产生的干眼症症状更低（p = 0.018），在图片观看时的自发性眨眼频率也比 ClearCare（p = 0.014）和 ReNu（p = 0.041）低。在阅读时，ClearCare 的眨眼频率比 ReNu（p = 0.026）和对照（p = 0.024）高。与 Opti-Free（p = 0.007）、ReNu（p = 0.009）和 ClearCare（p = 0.013）相比，对照（日抛隐形眼镜）在眨眼前的视觉辨别时间更长。
LCS 以不同的方式影响眨眼频率、主观干眼症症状和视觉辨别速度。与不含润湿剂的 LCS 相比，具有润湿剂的 LCS 导致眨眼次数明显减少，同时为隐形眼镜佩戴者提供更好的眼部舒适度。具有润湿剂的 LCS 与佩戴日抛隐形眼镜相比，也能获得更好的视觉表现。这可能是因为改善了泪膜质量。
