Regional Cancer Center, Uppsala University Hospital, Uppsala, Sweden.
J Clin Oncol. 2012 Aug 10;30(23):2853-60. doi: 10.1200/JCO.2011.41.4375. Epub 2012 Jul 9.
We examined changes in working time 16 months after a breast cancer diagnosis and identified factors associated with job discontinuation and/or decreased working time.
This was a population-based cohort study with 735 patients identified in the Regional Breast Cancer Quality Register of Central Sweden. The study sample consisted of 505 women (age < 63 years at diagnosis) who completed questionnaires at baseline and at follow-up (on average 4 and 16 months after diagnosis, respectively). Clinical register data and questionnaire data on sociodemographic factors were obtained at baseline. Self-reported work-related data were obtained at follow-up. Odds ratios were estimated by using logistic regression models.
Compared with prediagnosis working time, 72% reported no change in working time, 2% reported an increase, 15% reported a decrease, and 11% did not work at follow-up. Chemotherapy increased the likelihood (odds ratio [OR], 2.45; 95% CI, 1.38 to 4.34) of job discontinuation/decreased working time. Among chemotherapy recipients, associated factors included full-time work prediagnosis (OR, 3.25; 95% CI, 1.51 to 7.01), cancer-related work limitations (OR, 5.26; 95% CI, 2.30 to 12.03), and less value attached to work (OR, 3.69; 95% CI, 1.80 to 7.54). In the nonchemotherapy group, older age (OR, 1.09; 95% CI, 1.02 to 1.17) and less value attached to work (OR, 5.00; 95% CI, 2.01 to 12.45) were associated with the outcome.
The majority of women treated for breast cancer returned to their prediagnosis working time. Chemotherapy and cancer-related work limitations are important factors to take into account in identifying women in need of support. Moreover, it is important to consider the woman's own valuation of labor market participation.
我们研究了乳腺癌诊断后 16 个月工作时间的变化，并确定了与工作中断和/或工作时间减少相关的因素。
这是一项基于人群的队列研究，在瑞典中部地区乳腺癌质量登记处确定了 735 名患者。研究样本包括 505 名女性（诊断时年龄<63 岁），她们在基线和随访时（分别平均在诊断后 4 个月和 16 个月）完成了问卷调查。在基线时获得了临床登记数据和关于社会人口因素的问卷数据。在随访时获得了自我报告的与工作相关的数据。使用逻辑回归模型估计了比值比。
与诊断前的工作时间相比，72%的人报告工作时间没有变化，2%的人报告工作时间增加，15%的人报告工作时间减少，11%的人在随访时没有工作。化疗增加了工作中断/工作时间减少的可能性（比值比[OR]，2.45；95%置信区间[CI]，1.38 至 4.34）。在接受化疗的患者中，相关因素包括诊断前全职工作（OR，3.25；95%CI，1.51 至 7.01）、与癌症相关的工作限制（OR，5.26；95%CI，2.30 至 12.03）和对工作的重视程度较低（OR，3.69；95%CI，1.80 至 7.54）。在非化疗组中，年龄较大（OR，1.09；95%CI，1.02 至 1.17）和对工作的重视程度较低（OR，5.00；95%CI，2.01 至 12.45）与该结果相关。
大多数接受乳腺癌治疗的女性恢复了诊断前的工作时间。化疗和与癌症相关的工作限制是确定需要支持的女性的重要因素。此外，考虑女性自身对劳动力市场参与的重视程度也很重要。
