从盐芥基因组中洞察耐盐性。
Insights into salt tolerance from the genome of Thellungiella salsuginea.
机构信息
State Key Laboratory of Plant Genomics, National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
出版信息
Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12219-24. doi: 10.1073/pnas.1209954109. Epub 2012 Jul 9.
Abstract
Thellungiella salsuginea, a close relative of Arabidopsis, represents an extremophile model for abiotic stress tolerance studies. We present the draft sequence of the T. salsuginea genome, assembled based on ~134-fold coverage to seven chromosomes with a coding capacity of at least 28,457 genes. This genome provides resources and evidence about the nature of defense mechanisms constituting the genetic basis underlying plant abiotic stress tolerance. Comparative genomics and experimental analyses identified genes related to cation transport, abscisic acid signaling, and wax production prominent in T. salsuginea as possible contributors to its success in stressful environments.
摘要
盐芥（Thellungiella salsuginea）是拟南芥的近亲，是一种用于研究非生物胁迫耐受性的极端环境模式生物。我们提供了盐芥基因组的草图序列，该序列基于至少 28457 个基因的 7 条染色体，组装后的测序深度约为 134 倍。该基因组为植物非生物胁迫耐受性的遗传基础中构成防御机制的本质提供了资源和证据。比较基因组学和实验分析鉴定了与阳离子转运、脱落酸信号转导和蜡质合成相关的基因，这些基因在盐芥中较为显著，可能是其在胁迫环境中成功的原因之一。
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