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经过长时间潜伏期后的再激活发生在哪里?

Where is reactivation after a long latency?

作者信息

Hoshino Chisho, Yamabe Akane

机构信息

General Internal Medicine, Ohta-Nishinouchi Hospital, Koriyama City, Japan.

出版信息

BMJ Case Rep. 2012 Jul 9;2012:bcr0120125538. doi: 10.1136/bcr.01.2012.5538.

DOI:10.1136/bcr.01.2012.5538
PMID:22778449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3416985/
Abstract

The authors present a 90-year-old woman with unilateral glossopharyngeal, vagal and spinal accessory cranial nerve palsy along with pharyngeal and laryngeal vesicular eruptions. She was diagnosed with herpes zoster based on PCR testing on vesicular fluid for varicella-zoster virus (VZV). Reactivation of VZV in the head and neck region can cause life-threatening neurologic sequelae. Clinicians should be alert to the possibility of herpes zoster in a case of unilateral multiple cranial neuropathies and rapid combination therapy with acyclovir and corticosteroid should be initiated.

摘要

作者报告了一名90岁女性,患有单侧舌咽神经、迷走神经和副神经颅神经麻痹,同时伴有咽喉部水疱样皮疹。根据对水疱液进行水痘-带状疱疹病毒(VZV)的PCR检测,她被诊断为带状疱疹。VZV在头颈部区域的重新激活可导致危及生命的神经后遗症。对于单侧多发性颅神经病变的病例,临床医生应警惕带状疱疹的可能性,并应立即开始使用阿昔洛韦和皮质类固醇进行联合快速治疗。

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Where is reactivation after a long latency?经过长时间潜伏期后的再激活发生在哪里?
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本文引用的文献

1
Varicella zoster virus infection of the pharynx and larynx with multiple cranial neuropathies.水痘-带状疱疹病毒感染咽和喉伴多发性颅神经病。
Laryngoscope. 2011 Aug;121(8):1627-30. doi: 10.1002/lary.21859.
2
Varicella-zoster virus reactivation from multiple ganglia: a case report.水痘-带状疱疹病毒从多个神经节重新激活:一例报告
J Med Case Rep. 2009 Sep 14;3:9134. doi: 10.4076/1752-1947-3-9134.
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Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP).带状疱疹的预防:免疫实践咨询委员会(ACIP)的建议。
MMWR Recomm Rep. 2008 Jun 6;57(RR-5):1-30; quiz CE2-4.
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Unilateral associated laryngeal paralysis due to varicella-zoster virus: virus antibody testing and videofluoroscopic findings.水痘-带状疱疹病毒所致单侧相关性喉麻痹:病毒抗体检测及电视荧光透视检查结果
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Presence of VZV and HSV-1 DNA in human nodose and celiac ganglia.人类结状神经节和腹腔神经节中水痘带状疱疹病毒(VZV)和单纯疱疹病毒1型(HSV-1)DNA的存在情况。
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Ramsay Hunt syndrome.拉姆齐·亨特综合征
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7
Treatment of Ramsay Hunt syndrome with acyclovir-prednisone: significance of early diagnosis and treatment.阿昔洛韦联合泼尼松治疗拉姆齐·亨特综合征:早期诊断与治疗的意义
Ann Neurol. 1997 Mar;41(3):353-7. doi: 10.1002/ana.410410310.
8
Cranial nerve ischaemic arterial syndromes. A review.颅神经缺血性动脉综合征。综述。
Brain. 1986 Feb;109 ( Pt 1):207-16. doi: 10.1093/brain/109.1.207.