Shehab Abdulla, Al-Dabbagh Bayan, Almahmeed Wael, Bustani Nazar, Agrawal Amrish, Yusufali Afzal, Wassef Adel, Alnaeemi Abdulla, Alsheikh-Ali Alawi A
Department of Internal Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain, UAE.
ScientificWorldJournal. 2012;2012:698597. doi: 10.1100/2012/698597. Epub 2012 Jun 18.
We describe the baseline characteristics, management, and in-hospital outcomes of patients in the United Arab Emirates (UAE) with DM admitted with an acute coronary syndrome (ACS) and assess the influence of DM on in-hospital mortality. Data was analyzed from 1697 patients admitted to various hospitals in the UAE with a diagnosis of ACS in 2007 as part of the 1st Gulf RACE (Registry of Acute Coronary Events). Of 1697 patients enrolled, 668 (39.4%) were diabetics. Compared to patients without DM, diabetic patients were more likely to have a past history of coronary artery disease (49.1% versus 30.1%, P < 0.001), hypertension (67.2% versus 36%, P < 0.001), and prior revascularization (21% versus 11.4%, P < 0.001). They experienced more in-hospital recurrent ischemia (8.5% versus 5.1%; P = 0.004) and heart failure (20% versus 10%; P < 0.001). The mortality rate was 2.7% for diabetics and 1.6% for nondiabetics (P = 0.105). After age adjustment, in-hospital mortality increased by 3.5% per year of age (P = 0.016). This mortality was significantly higher in females than in males (P = 0.04). ACS patients with DM have different clinical characteristics and appear to have poorer outcomes.
我们描述了阿拉伯联合酋长国（UAE）患有糖尿病且因急性冠状动脉综合征（ACS）入院患者的基线特征、治疗情况及住院结局，并评估糖尿病对住院死亡率的影响。作为首届海湾急性冠状动脉事件注册研究（Gulf RACE）的一部分，我们分析了2007年阿联酋各医院收治的1697例诊断为ACS患者的数据。在纳入的1697例患者中，668例（39.4%）为糖尿病患者。与非糖尿病患者相比，糖尿病患者更有可能有冠状动脉疾病病史（49.1%对30.1%，P<0.001）、高血压（67.2%对36%，P<0.001）及既往血运重建史（21%对11.4%，P<0.001）。他们在住院期间经历更多的反复缺血（8.5%对5.1%；P=0.004）和心力衰竭（20%对10%；P<0.001）。糖尿病患者的死亡率为2.7%，非糖尿病患者为1.6%（P=0.105）。年龄调整后，住院死亡率每年增加3.5%（P=0.016）。女性的死亡率显著高于男性（P=0.04）。患有糖尿病的ACS患者具有不同的临床特征，且结局似乎更差。
